AstraZeneca Posted August 4, 2026

Senior HVAC Maintenance Technician

Santa Monica, California, United States of America Full time
Manufacturing & CMC Senior

AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

What you’ll do

Lead preventive/predictive/corrective maintenance across AHUs, chillers, boilers, heat exchangers, VAVs, exhaust, dehumidifiers, and split systems, owning temperature, humidity, airflow, and pressurization in GMP spaces.

Ensure cleanroom compliance with ISO 14644: HEPA integrity, airflow patterns, recovery times, and differential pressures; support aseptic areas and gowning zones.

Optimize and troubleshoot BMS/EMS/SCADA (Siemens, Allen-Bradley, Johnson Controls): tune PID loops, rationalize alarms, adjust sequences of operation, and document via change control.

Coordinate calibration (temperature, RH, pressure, flow) and support IQ/OQ/PQ with solid validation documentation.

Drive investigations and CAPA using RCA methods (5-Why, Fishbone) and maintain impeccable cGMP/GDP records and SOPs.

Champion audit readiness (FDA/EU GMP) and keep systems in a validated state.

Improve energy and performance: VFDs, heat recovery, demand-based ventilation, and smart control strategies.

Plan and execute outages/turnarounds/capital projects with contractors, materials, and risk assessments.

Lead safety culture (LOTO, confined space, hot work, arc-flash; EPA 608 refrigerants) and mentor junior techs.

Manage spares and CMMS workflows; partner closely with Quality, Manufacturing, Engineering, Validation, and Operations.

Impact that matters: Your work directly supports compliant manufacturing and product quality.

Variety and ownership: Complex systems, cross-functional collaboration, and continuous improvement.

Growth and mentorship: Be the SME and coach for a high-performing team.

Minimum Requirements:

High school diploma/GED

6–10+ years in HVAC maintenance, including 3–5 years in pharma/biotech or regulated GMP environments

Cleanroom HVAC experience is essential.

GMP know‑how: ISO cleanroom classifications, airflow visualization/smoke studies, pressurization cascades, aseptic requirements.

Technical strengths: AHUs/chillers/boilers/hydronics, humidity control, HEPA; strong controls/BMS proficiency (PID, trends, data integrity).

Validation: Sensor calibration, IQ/OQ/PQ, GDP, CAPA, Change Control.

Diagnostics: Advanced troubleshooting, basics of vibration analysis and thermography; instrumentation (anemometers, micromanometers, particle counters, data loggers).

Soft skills: Clear communication, teamwork, stakeholder management, decisive under time pressure, meticulous documentation.

Physical: Lift 50 lbs, ladders/heights/mechanical spaces, PPE for labs/cleanrooms, after-hours/on-call rotation.

Desired:

Technical diploma/apprenticeship in HVAC/Mechanical/Building Services;

Bachelor’s in Mechanical/Building is a plus.

Certifications: Safety training preferred; manufacturer training on chillers/controls and GxP/cleanroom courses are a plus.

Interested? Apply to join our Technical Operations team in Santa Monica or Tarzana and help us keep mission-critical environments running flawlessly.

The annual base pay (or hourly rate of compensation) for this position ranges from $71,749.60 - 107,624.40 . Our positions offer eligibility for various incentives, an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

04-Aug-2026

Closing Date

21-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Job details

Seniority
Senior
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Santa Monica, California, United States of America
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 373 comparable Senior Manufacturing & CMC roles across 53 biopharma companies.

373Comparable roles tracked
345Currently active
53Companies hiring similar roles
20Countries represented

Salary context

175 of 373 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $222,900 (median $142,325)

Where these roles are based

Top locations among the 373 comparable roles

United States267
India37
Ireland10
Singapore10
Netherlands7
Switzerland6

+ 14 more countries

Seniority mix

373 of 373 peers have a known seniority level

Senior250
Principal79
Associate Director44

Therapeutic area mix

0 of 373 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

No peers with a known therapeutic area yet.

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly San Diego, California, United States of America Senior
Same function Same seniority Same country
60%similar
Merck Rahway, New Jersey, United States of America Senior
Same function Same seniority Same country
60%similar
Seagen Inc Washington – Bothell, United States Senior
Same function Same seniority Same country
60%similar
Pfizer Groton, United States Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Sr. Scientist - Lab Automation Scientist
Lilly · San Diego, California, United States of America · Senior
Function Therapeutic area Seniority Country
60%
Senior Scientist, Process Development
Pfizer · Groton, United States · Senior
Function Therapeutic area Seniority Country
60%
Senior Scientist, Biologics Purification II
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
60%
Senior Electrical Engineer, Combination Product Development
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.