Senior Engineer I, Manufacturing Sciences - Purification

About This Role 

The Senior Engineer I, Manufacturing Sciences serves as a key scientific resource supporting biologics purification for drug substance manufacturing at Biogen’s RTP facility. This role enables successful production of biopharmaceuticals by designing and executing laboratory studies, leading downstream process transfers into GMP manufacturing, and providing scientific support to ongoing commercial operations.

What You’ll Do 

Provide deep technical expertise in biologics purification: chromatographic separations, viral filtration, and UF/DF to support technology transfer and process improvement initiatives

Design, plan, execute, and document laboratory studies to improve process robustness, enhance process understanding, and troubleshoot manufacturing issues

Lead cross-functional project teams and collaborate with Technical Development, Engineering, and GMP Manufacturing

Support downstream GMP operations, including process transfer activities and ongoing manufacturing campaigns

Serve as technical SME for investigations, performing root cause analysis and implementing effective corrective and preventive actions (CAPAs)

Represent manufacturing in change controls, continuous improvement initiatives, capital projects, and new component introductions

Support process validation activities, including batch execution and authoring technical summary reports

Analyze manufacturing data and experimental results, clearly communicating insights and recommendations to stakeholders

Who You Are 

You are a hands-on, scientifically driven problem solver with experience in mammalian cell culture. You thrive in collaborative environments, enjoy working with complex data, and are motivated to improve manufacturing processes through practical, data-driven solutions.

Required Skills

Bachelor’s degree in relevant scientific or technical fields from an accredited college or university

At minimum 4 years of directly relevant industry or industry-adjacent experience

Familiarity with biopharmaceutical manufacturing and/or downstream processing

Previous experience with some or all of the following: design experiments, analyze data, and/or execute laboratory studies

Willingness and ability to work on-site more frequently during training periods, critical projects, audits, etc.

Preferred skills

Bachelor’s degree in engineering or life science

Demonstrated experience leading complex scientific projects related to purification

Previous experience performing root cause analysis and risk-based technical assessments

Experience supporting deviations, change controls, CAPAs, and regulatory documentation

Prior experience acting as a technical lead or SME within a manufacturing support organization

Job Level: Professional

Additional Information

The base compensation range for this role is: $98,000.00-$127,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:

Medical, Dental, Vision, & Life insurances

Fitness & Wellness programs including a fitness reimbursement

Short- and Long-Term Disability insurance

A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)

Up to 12 company paid holidays + 3 paid days off for Personal Significance

80 hours of sick time per calendar year

Paid Maternity and Parental Leave benefit

401(k) program participation with company matched contributions

Employee stock purchase plan

Tuition reimbursement of up to $10,000 per calendar year

Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.  Read on  to learn more about our Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.