Amgen Technology Pvt Ltd. Posted May 6, 2026

Principal Systems Engineer – Clinical Computation Platform

Hyderabad, India Full time
Information Technology Principal

Amgen Technology Pvt Ltd. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Clinical

Job Description

ABOUT AMGEN

Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier,   fuller   and longer. We discover, develop,   manufacture   and deliver innovative medicines to help millions of patients. Amgen helped   establish   the biotechnology industry more than 40 years ago and   remains   on the   cutting-edge   of innovation, using technology and human genetic data to push beyond   what’s   known today.

ABOUT THE ROLE

Role Description:

The   role   is responsible for   the design, integration, and management of complex systems that encompass both hardware and software components   into the   organization’s   cloud   infrastructure .   Th is individual   will   be responsible for   all activities related to handling and supporting   the   Business and platforms including system administration, as well as incorporating   new technologies   under the challenge of a sophisticated and constantly evolving technology landscape .   This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements.

Roles & Responsibilities:

Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization

Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines

Support selected efforts to design, build, and develop rapid   Proof-of-Concept   (POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered

Develop and design systems architecture, ensuring   that   it meets both current and future needs of the organization

Integrate hardware and software components into a cohesive system that meets functional and performance requirements

Perform system testing and validation to ensure all components function correctly and efficiently

Optimize   system performance and troubleshoot any issues that arise during system operation

Create and   maintain   comprehensive documentation of systems design, configurations, and procedures

Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems

Monitor and   maintain   systems to ensure they continue to   operate   effectively and efficiently

Implement automation tools and processes to improve the efficiency and reliability of   the system

Conduct   training   and workshops   for business teams   to share best   practices in the industry.

Basic Qualifications and Experience:

Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science,   IT   or related field

Functional Skills:

Must-Have Skills :

Experience   in cloud platforms   including   AWS

Experience with container technologies like Docker and Kubernetes

Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements

Experience with translating business requirements to technical requirements and recommend solutions for automation

Proficiency   in programming languages   including   R,    Python

Experience and   strong knowledge of   POSIT Tools and Se rvices

Strong understanding of software development methodologies, including Agile and Scrum

Good-to-Have Skills:

Experience with DevOps tools and practices

Strong understanding of systems engineering processes and methodologies

Experience with systems integration and validation

Knowledge of Clinical Development domain

Professional Certifications :

Scaled Agile Framework ( SAFe ) for Teams (preferred)

Soft Skills:

Excellent analytical and troubleshooting skills

Strong verbal and written communication skills

Ability to work effectively with global, virtual teams

High degree of initiative and self-motivation

Ability to manage multiple priorities successfully

Team-oriented, with a focus on achieving team goals

Strong presentation and public speaking skills

Shift Information:

This position requires you to work a later shift and may be   assigned   a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as   required   based on business requirements.

EQUAL OPPORTUNITY STATEMENT

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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Job details

Seniority
Principal
Function
Information Technology
Therapeutic area
Not listed
Location
Hyderabad, India
Employment type
Full time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 367 comparable Principal Information Technology roles across 36 biopharma companies.

367Comparable roles tracked
343Currently active
36Companies hiring similar roles
20Countries represented

Salary context

46 of 367 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Data Security Engineer (Insider Risk Management – Engineering) · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Director, Product Management · $223,642/yr – $305,200/yr
Peer group range $0 – $264,421 (median $151,100)

Where these roles are based

Top locations among the 367 comparable roles

India196
United States75
Spain17
Poland14
Portugal11
Greece9

+ 14 more countries

Seniority mix

367 of 367 peers have a known seniority level

Senior290
Principal49
Director28

Therapeutic area mix

1 of 367 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Bristol-Myers Squibb Business Services India Private Limited Hyderabad, India Principal
Same function Same seniority Same country
60%similar
Amgen Technology Pvt Ltd. Hyderabad, India Principal
Same function Same seniority Same country
60%similar
Amgen Technology Pvt Ltd. Hyderabad, India Principal
Same function Same seniority Same country
60%similar
Amgen Technology Pvt Ltd. Hyderabad, India Principal
Same function Same seniority Same country
60%similar
Amgen Technology Pvt Ltd. Hyderabad, India Principal
Same function Same seniority Same country
60%similar
Amgen Technology Pvt Ltd. Hyderabad, India Principal
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Principal AI Engineer
Bristol-Myers Squibb Business Services India Private Limited · Hyderabad, India · Principal
Function Therapeutic area Seniority Country
60%
Principal IS Architect, Anaplan
Amgen Technology Pvt Ltd. · Hyderabad, India · Principal
Function Therapeutic area Seniority Country
60%
Principal IS Architect – Storage & Backup
Amgen Technology Pvt Ltd. · Hyderabad, India · Principal
Function Therapeutic area Seniority Country
60%
Principal Machine Learning Engineer - Forecasting
Amgen Technology Pvt Ltd. · Hyderabad, India · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.