MSL – ATTR/Cardiovascular - San Francisco, CA
About this opportunity
At AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and collaborating to make the impossible a reality. We focus on the power of science to address unmet patient needs worldwide. We commit to areas where we can truly change the course of medicine and bring ambitious new ideas to life.
As an Amyloidosis (ATTR) Medical Science Liaison (MSL), you’ll play a pivotal role in channeling our scientific expertise to positively impact patient care.
About the BioPharmaceuticals Business Unit (BBU)
The BBU develops and drives therapeutic area and product strategies that address unmet patient needs globally. We integrate commercial, market access, medical, digital, and corporate functions to drive scientific innovation and commercial excellence in respiratory, cardiovascular, renal, and diabetes disease areas.
Why This Role Matters
As an ATTR MSL, you will be part of AstraZeneca’s mission to transform clinical practice through science and technology. You’ll partner with healthcare professionals to reduce acute episodes, disease complications, hospital admissions, and premature death. Through innovation, leadership, and sustainability, we put patients first.
What You’ll Do
In this field-based role covering San Francisco (San Francisco CA, Sacramento CA, Stanford CA) and surrounding areas, you will:
Engage and build relationships: Develop and maintain strong connections with heart failure specialists, cardiologists, and key opinion leaders (KOLs) in cardiovascular and amyloid disease areas
Scientific exchange and insights: Collect, analyze, and share evidence-based insights while leveraging territory relationships to accelerate knowledge transfer and influence clinical practice
ATTR-CM expertise: Apply prior experience or meaningful exposure to ATTR cardiomyopathy in field activities and translate complex scientific data into clear, clinician-ready insights
Education and collaboration: Support clinician education, deliver presentations, and provide clinical guidance at regional and national meetings
Patient-focused impact: Identify opportunities to improve patient outcomes and provide actionable insights to internal teams
Regulatory and product knowledge: Respond to inquiries with clear, balanced scientific information while ensuring compliance with regulatory and company standards
Continuous learning: Stay current on disease state management, emerging therapies, and the competitive landscape
Development Opportunities
Structured onboarding and continuous learning programs
Exposure to clinical development activities and therapeutic brand strategies
Opportunities to lead projects within the medical team and develop leadership skills over time
Minimum Requirements
Bachelor’s Degree in a clinical or scientific field
1–2 years of clinical experience in ATTR, Heart Failure, Cardiology and/or pharmaceutical experience with exposure to cardiovascular or amyloidosis disease areas, including KOL engagement, scientific exchange, and territory-based field activities
Understanding of healthcare delivery systems, payer structures, and treatment pathways
Clinical experience in the relevant therapeutic area and ability to build professional relationships
Strong communication skills to convey complex scientific information clearly
Demonstrated ability to lead projects and influence cross-functional teams
Knowledge of regulatory and compliance requirements related to medical affairs
Ability to travel 50–70% (varies by geography), including weekends and overnights
Desirable Requirements
Advanced degree in a clinical or scientific field (MD, PharmD, PhD, NP, PA)
2+ years of pharmaceutical industry experience / previous MSL experience in ATTR
Rare Disease and/or Cardiology experience
Ability to build and leverage relationships to influence outcomes that improve patient care
The annual base pay for this position ranges from $160,396 – $240,594 USD. Our positions offer eligibility for various incentives, including short-term bonuses, equity-based awards for salaried roles, and commissions for sales roles. Benefits include retirement programs, paid time off, and health, dental, and vision coverage in accordance with applicable plans.
Why AstraZeneca:
Here, your strategic voice shapes how science reaches people. We bring diverse experts together early to spot opportunities, learn fast, and build evidence that stands up to real-world payer scrutiny, so innovative medicines can reach millions who need them. You will join a resilient, kind, and ambitious team that pairs cutting-edge analytics with strong storytelling and negotiation, working with autonomy and deep collaboration to create sustainable access across regions and indications. This is where forward-looking minds influence the healthcare ecosystem, turning insights into action and action into impact. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Call to Action:
Step into a role where your leadership turns evidence into access, seize this opportunity to shape the future of payer strategy and patient outcomes today!
Date Posted
11-Aug-2026
Closing Date
24-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
Job details
How this role compares
Computed from every other active Medical Affairs role in our database, not just this employer's listings.
We currently track 924 comparable Medical Affairs roles across 130 biopharma companies.
Salary context
175 of 924 peers report a salary range (USD, annualized)
Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.
Where these roles are based
Top locations among the 924 comparable roles
+ 52 more countries
Seniority mix
502 of 924 peers have a known seniority level
Therapeutic area mix
325 of 924 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.