AstraZeneca Posted August 11, 2026

Manager, US Sales Incentive Compensation

Boston, Massachusetts, United States of America Full time
Commercial & General Management Manager

AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Manager, US Sales Incentive Compensation

Location: Boston, MA (hybrid 3x a week)

Introduction to the role

The Manager, Incentive Compensation will play a critical role in the success of Alexion’s Incentive Compensation strategy and the Business Operations and Commercial Effectiveness organization. The role will report into the Sr. Director, US Sales Incentive Compensation and will partner closely with other members of the Incentive Compensation team.

The Manager will be essential in optimizing the sales incentive compensation programs for the Alexion US Commercial field-based sales teams by supporting existing incentive compensation programs, generating insights, and collaborating with internal technology partners.  Additionally, the Incentive Compensation Manager may be involved in communicating and educating employees on the incentive programs and resolving any related issues or concerns.

What you’ll do:

Contributes to the design and administration of all field-based compensation programs for the Alexion US Commercial organization that recognize and reward employee performance and drive business results.

Collaborates with technology partners to define system business specifications,  automate performance reporting and incentive calculations, and implement quality control measures to ensure high level of data and reporting accuracy.

Supports the ongoing monitoring and analysis of incentive plans and manages field inquiries related to incentive compensation.

Contributes to the complex research and analysis of rewards and incentive compensation programs in support of business objectives.

Supports existing programs, generating insights, and collaborating with internal teams.

Ensures compliance with Alexion processes touching incentive compensation.

Requirements:

Bachelor’s degree required (Business, Finance, Math, or related major is preferred).

At least 4 years of experience in sales performance analytics and reporting.

Demonstrated understanding of various incentive compensation plans, including but not limited to commission, goal, and MBO plan designs.

Analytics skills inclusive of advanced Microsoft Excel capabilities.

Ability to translate business need to technical resources / collaborators and drive outcomes.

Ability to employ AI tools to generate insights from complex and disparate data sources.

Detail oriented, strong problem-solving skills with a sense of urgency.

Ability to lead projects independently and communicate with leadership collaborators.

Excellent communication and presentation skills to all levels in the organization.

Confidence in requirements gathering and engaging with partners at all levels.

The duties of this role are generally conducted in an office environment.  As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Desirable:

At least 2 years of experience in sales incentive compensation design and analytics – ideally within the pharmaceutical/biotech industry.

Experience in advanced analytics in healthcare, research /consulting, or pharmaceutical/biotech company

Experience with specialty and/or orphan/rare disease therapies.

Expertise in analytical tools such as SQL, QLIK, Tableau

Demonstrated ability to work independently in a lean, dynamic and nimble environment and adjust to changing priorities.

Capability to work on multiple projects and meet timelines.

Effective interpersonal skills: ability to develop rapport and credibility with field and home office personnel including management.

At Alexion, you will find a collaborative culture that encourages innovation and a diverse environment where your contributions are valued. You will have the opportunity to be at the forefront of rare disease research and make a meaningful difference in patients' lives.

Ready to lead and encourage? Apply now and take the first step towards a fulfilling career at Alexion, AstraZeneca Rare Disease.

#LI-Hybrid

The annual base pay for this position ranges from $100,312.80 - $150,469.20 USD. Our positions offer eligibility for various incentives, an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

11-Aug-2026

Closing Date

24-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Job details

Seniority
Manager
Function
Commercial & General Management
Therapeutic area
Not listed
Location
Boston, Massachusetts, United States of America
Employment type
Full time

How this role compares

Computed from every other active Commercial & General Management role in our database, not just this employer's listings.

We currently track 9 comparable Manager Commercial & General Management roles across 3 biopharma companies.

9Comparable roles tracked
2Currently active
3Companies hiring similar roles
3Countries represented

Salary context

1 of 9 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Only peer reporting · Associate Director, PDM Strategy · Gilead Sciences, Inc. $182,070/yr – $235,620/yr
Peer group range $208,845 – $208,845 (median $208,845)

Where these roles are based

Top locations among the 9 comparable roles

United States7
Poland1
Japan1

Seniority mix

9 of 9 peers have a known seniority level

Associate Director7
Manager2

Therapeutic area mix

1 of 9 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
AstraZeneca Gaithersburg, Maryland, United States of America Manager
Same function Same seniority Same country
50%similar
Gilead Sciences, Inc. Foster City, United States Associate Director
Same function Adjacent seniority Same country
50%similar
AstraZeneca Boston, Massachusetts, United States of America Associate Director
Same function Adjacent seniority Same country
50%similar
AstraZeneca Boston, Massachusetts, United States of America Associate Director
Same function Adjacent seniority Same country
50%similar
AstraZeneca Wilmington, Delaware, United States of America Associate Director
Same function Adjacent seniority Same country
50%similar
AstraZeneca Boston, Massachusetts, United States of America Associate Director
Same function Adjacent seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Manager, IO Forecasting
AstraZeneca · Gaithersburg, Maryland, United States of America · Manager
Function Therapeutic area Seniority Country
50%
Associate Director, Incentive Compensation
AstraZeneca · Boston, Massachusetts, United States of America · Associate Director
Function Therapeutic area Adjacent seniority Country
50%
Global Analytics & Insights, Associate Director - Oncology (Lung)
AstraZeneca · Gaithersburg, Maryland, United States of America · Associate Director
Function Therapeutic area Adjacent seniority Country
35%
【AstraZeneca】【CET】Cutomer Experience & IT, Associate Director Data Scientist
AstraZeneca · Kita-ku, Osaka, Japan · Associate Director
Function Therapeutic area Adjacent seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.