Roche Posted August 8, 2026

Lead AI Engineer (Agentic Systems)

Madrid, Spain FULL_TIME
Information Technology

Roche is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

At Roche, we believe the next frontier of healthcare innovation hinges on our ability to effectively connect, orchestrate, and leverage our global Clinical and Commercial Intelligence. Generative AI has moved beyond simple chat interfaces; we are building an enterprise-wide ecosystem of autonomous, reasoning, and self-improving agents to solve unprecedented challenges in the Diagnostics Commercial space.

As the Lead AI Engineer , you will serve as the principal technical authority and strategic catalyst for our next-generation AI architecture. This is a high-impact, senior-level role demanding both technical excellence and strategic leadership. You will define the global blueprint for how multi-agent systems interact, orchestrate complex workflows, connect with legacy enterprise data, and execute autonomous decisions safely. Your leadership will directly transform Roche Diagnostics' commercial agility, pricing modeling, market-access strategies, and international customer engagement frameworks.

The Opportunity

Define the Enterprise Blueprint: Act as the chief architect and technical visionary for Roche’s Commercial GenAI platform strategy. Design the core multi-agent orchestration blueprints, common state-management protocols, and shared tool-use boundaries across the global diagnostics enterprise.

Drive Cutting-Edge R&D to Production: Lead the technical evaluation and strategic adoption of emerging agentic paradigms (e.g., hierarchical multi-agent teams, reflection loops, knowledge semantic models, and complex orchestration architectures using frameworks like LangGraph, AutoGen, or custom orchestrators).

Champion Engineering Excellence & Governance: Establish rigorous enterprise-level standards for LLMOps and Agent-Ops. Define global frameworks for agentic benchmarking, fallback mechanics, semantic caching, automated cost containment, and guardrailing to prevent runaway autonomous loops.

Act as a Catalyst Partner: Work hand-in-hand with senior business executives, global product heads, and legal/compliance councils to transform multi-million dollar business problems into robust, highly compliant, agent-driven software realities.

Mentor and Upskill: Cultivate a world-class community of practice. While you may not have traditional direct HR reports initially, you will exert significant influence through matrixed leadership, mentoring senior developers and AI engineers across our global digital hubs.

Who You Are

You are a seasoned software architect and a pioneer in the AI engineering space. You possess a unique blend of deep technical mastery, architectural pragmatism, and executive-level communication skills. You thrive when translating ambiguous enterprise challenges into deterministic, scalable software systems, and you are passionately driven by the opportunity to apply AI to a business that saves lives.

Education & Qualifications:

Postgraduate degree (Master’s or Ph.D. preferred) in Computer Science, Software Engineering, AI/Machine Learning, or an equivalent technical field.

Technical Experience & Capabilities:

Senior Engineering Track Record: 8+ years of hands-on software engineering experience, including at least 3+ years specifically architecting, deploying, and scaling complex Generative AI and LLM workflows in enterprise production environments.

Orchestration Expertise: Deep, production-tested experience with state-management in agentic networks (e.g., building directed acyclic graphs for LLM reasoning, handling agent-to-agent negotiation loops, and implementing persistent cognitive memory).

System Design & Security: Outstanding expertise in microservices architecture, secure API orchestration, semantic routing, and cloud-native scaling (AWS/Azure/GCP). Highly proficient in advanced vector search, graph databases (e.g., Neo4j), and hybrid retrieval mechanisms.

Rigorous Evaluation Mindset: Proven track record of designing custom evaluation frameworks for non-deterministic AI systems, balancing tradeoffs between latency, execution cost, token limits, and reasoning accuracy.

Regulated Industry Acumen: Prior experience designing automated systems within highly regulated frameworks (Healthcare, Finance, or Aerospace) is highly desirable. An intimate understanding of AI safety, algorithmic bias mitigation, and data privacy compliance is required.

Influential Leadership: Exceptional ability to influence without formal authority, present complex technical roadmaps to non-technical C-suite stakeholders, and drive alignment across cross-functional matrix organizations.

What We Offer

At Roche, we foster an environment built on trust, psychological safety, and radical innovation. We offer an executive-level total rewards package, including highly competitive base compensation, performance-driven bonuses, comprehensive health and wellness benefits, flexible executive hybrid work arrangements, and the profound satisfaction of steering the digital transformation of a global healthcare leader.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination.

 

 

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.

Job details

Seniority
Not listed
Function
Information Technology
Therapeutic area
Not listed
Location
Madrid, Spain
Employment type
FULL_TIME

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 1097 comparable Information Technology roles across 55 biopharma companies.

1097Comparable roles tracked
1035Currently active
55Companies hiring similar roles
29Countries represented

Salary context

143 of 1097 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Data Security Engineer (Insider Risk Management – Engineering) · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Senior Director, Targets and Mechanisms Solutions · Pfizer $230,900/yr – $384,800/yr
Peer group range $0 – $307,850 (median $165,900)

Where these roles are based

Top locations among the 1097 comparable roles

India507
United States241
Spain105
Poland72
Portugal32
China13

+ 23 more countries

Seniority mix

612 of 1097 peers have a known seniority level

Senior290
Manager135
Associate52
Principal50
Associate Director39
Director28
Senior Director13
Intern/Fellow/Postdoc4
Executive/VP1

Therapeutic area mix

1 of 1097 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
Roche Sant Cugat del Vallès, Barcelona, Spain
Same function Same country
40%similar
Roche Sant Cugat del Vallès, Barcelona, Spain Senior
Same function Same country
40%similar
Novartis Barcelona Gran Vía, Spain
Same function Same country
40%similar
Novartis Barcelona Gran Vía, Spain Associate Director
Same function Same country
40%similar
Novartis Barcelona Gran Vía, Spain Associate Director
Same function Same country
40%similar
Novartis Barcelona Gran Vía, Spain Associate Director
Same function Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Lead Software Engineer (Rust)
Roche · Sant Cugat del Vallès, Barcelona, Spain · Seniority not listed
Function Therapeutic area Seniority Country
40%
Associate Director Business Analysis (GCO)
Novartis · Barcelona Gran Vía, Spain · Associate Director
Function Therapeutic area Seniority Country
40%
Snr. Specialist, Platform Services - Data, Digital & IT
Novartis · Barcelona Gran Vía, Spain · Seniority not listed
Function Therapeutic area Seniority Country
40%
Associate Director, Solution Design Expert (Advanced Therapies)
Novartis · Barcelona Gran Vía, Spain · Associate Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.