Senior Scientist, Membrane Protein Biochemistry
About this opportunity
Career Category
Scientific
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.
As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Scientist, Membrane Protein Biochemistry
What you will do
Let’s do this. Let’s change the world. In this vital role you will be part of an innovative integrative Protein Generation group within Discovery Protein Science, with responsibilities including (but not limited to) the design of strategies for recombinant production of polytopic membrane protein (MP) targets and their purification with detailed analytical characterization. This role will also include opportunities to develop MP platforms and capabilities that increase the success rates of large-molecule and small-molecule therapeutic discovery programs.
Key Responsibilities:
Independently devise and implement state-of-the-art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables
Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds
Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward
Additional responsibilities may include keeping current in membrane protein expertise, advising supervisors and colleagues to shape future membrane protein technology development strategies, and mentoring junior scientists and technical staff
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist we seek is a Researcher with these qualifications.
Basic Qualifications:
Doctorate degree PhD
OR
PharmD
OR
MD [and relevant post-doc experience]
OR
Master’s degree and 3 years of relevant laboratory experience
OR
Bachelor’s degree and 5 years of relevant laboratory experience
Preferred Qualifications:
Ph.D. plus relevant postdoctoral experience
Flexible problem-solving skills, as exemplified by a consistent track record of scientific accomplishments (e.g., peer-reviewed publications and/or patents)
Proven expertise with ÄKTA systems and analytical methods for membrane protein characterization using quality-focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry.
Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus
Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams in a fast-paced environment
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range
142,518.65USD -192,819.35 USD
Job details
How this role compares
Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.
We currently track 188 comparable Senior Drug Discovery & Preclinical Research roles across 30 biopharma companies.
Salary context
62 of 188 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 188 comparable roles
+ 6 more countries
Seniority mix
188 of 188 peers have a known seniority level
Therapeutic area mix
29 of 188 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.