Senior Scientist (all genders) - Biophysics and Analytics (Wuppertal-Aprath, North Rhine Westfalia, DE)

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.

Senior Scientist (all genders) - Biophysics and Analytics

In your role as a Senior Scientist (m/f/d) - Biophysics and Analytics y ou combine deep expertise in protein biophysics with a hands-on, drug-hunting mindset and the ability to generate high-impact experimental insights for discovery programs. You drive high-quality data generation at the bench while supporting scientific project delivery across modalities (small molecules, biologics, glue degraders, PROTACs, siRNA). Apply now to help advance our portfolio decisions with rigorous biophysical and analytical evidence.

YOUR TASKS AND RESPONSIBILITIES

Design, execute, and troubleshoot biochemical and biophysical assays to characterize proteins, with a strong focus on interaction analysis, quality control, and mechanism-of-action studies

Design and execute protein mass spectrometry workflows (intact mass analysis, peptide mapping, characterization of post-translational modifications and sequence variants) and integrate the data into project decisions

Plan, run, and analyze label-free binding experiments on SPR platforms (e.g., Biacore, Carterra), including kinetic, affinity, and epitope-binning/competition studies

Develop and validate fit-for-purpose biochemical and biophysical assays to support screening, hit validation, and lead optimization

Interpret complex datasets, present results and recommendations, and partner closely with discovery colleagues to embed biophysical insights into decision-making

Contribute to lab organization, platform ownership and maintenance (including MS and SPR), and continuous workflow improvements, including automation and high-throughput opportunities

Collaborate with highly skilled research associates and scientists across levels and interface with cross-functional teams (e.g., structural biology, protein engineering, chemical biology, in vitro assays)

Contribute to the digital agenda by optimizing workflows and generating/analyzing data to enable in silico experimentation and machine learning

take accountability in cross-functional teams across the discovery value chain in line with timelines and budget

WHO YOU ARE

Hold a PhD in biochemistry, biophysics, biotechnology, or a related discipline, ideally complemented by relevant industry experience (biotech/pharma, CRO, or academic collaboration)

Bring hands-on experience in protein mass spectrometry (e.g., intact mass, peptide mapping, PTM profiling) and familiarity with relevant data-analysis software

Stand out with demonstrated hands-on experience in biophysical methods for biomolecular interactions, especially SPR; experience with MST, ITC, DSF, or BLI is a strong plus

Have a solid foundation in protein biochemistry, including purification and quantitative analysis of recombinant proteins and approaches to understand protein structure, properties, and function

Demonstrate strong data analysis capabilities and the ability to translate experimental results into clear, project-relevant conclusions

Bring exposure to high-throughput and/or automated workflows for biophysical, biochemical, and MS-based assays

Have exposure to biologics or protein-based therapeutics (e.g., antibodies, Fc-fusion proteins) and feel confident working in a modality-agnostic discovery environment; deep biologics discovery experience is a plus

Combine excellent interpersonal and teamwork skills with high learning agility and strong self-organization

Fluent in English, both written and spoken, with strong communication and presentation skills; German language skills are a plus

WHAT WE OFFER

Our benefits package is flexible, appreciative, and tailored to your lifestyle, because: What matters to you, matters to us!

We ensure your financial stability with a competitive salary between 77.300€ and 93.800€ per year (full-time) plus a variable component. Your compensation is based on your qualifications, skills, and professional experience.

Whether it’s hybrid work models or part-time arrangements: Whenever it is possible, you will have the flexibility to work how, when and where it is best for you.

Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more.

We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues, as well as coaching and mentoring programs.

We promote health awareness and opportunities for selfcare through various measures, such as free health checks with the company doctor.

We embrace diversity by providing an inclusive work environment in which you are welcomed, supported, and encouraged to bring your whole self to work.

Be you! Be Bayer!

#LI-AMSEMEA

YOUR APPLICATION

This is your opportunity to tackle the world’s biggest challenges with us: Maintaining our health, feeding growing populations and slowing the rate of climate change. You have a voice, ideas and perspectives and we want to hear them. Because our success begins with you. Be part of something big. Be Bayer.

Bayer welcomes applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

Location:            ​ ​  ​   Germany : North Rhine Westfalia : Wuppertal-Aprath ​

​ ​ Division: ​               Pharmaceuticals ​

Reference Code:  879394 ​

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