Senior SAFe Program Manager / Release Train Engineer
About this opportunity
Career Category
Information Systems
Job Description
ABOUT AMGEN
Join Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas, Oncology, Inflammation, General Medicine, and Rare Disease, we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines that help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for solving complex problems, enabling high-performing teams, and driving meaningful business outcomes, you'll thrive as part of the Amgen team.
Join us and transform the lives of patients while transforming your career.
What you will do
Role Description
The Senior SAFe Program Manager / Release Train Engineer is a strategic Lean-Agile leader responsible for enabling successful execution across one or more Agile Release Trains (ARTs). This role partners closely with Product Management, Engineering, Architecture, Business stakeholders, and leadership teams to deliver high-value digital solutions while fostering a culture of collaboration, continuous improvement, and execution excellence.
As a servant leader, coach, and facilitator, the Senior RTE helps teams achieve higher levels of Agile maturity by facilitating Program Increment (PI) execution, managing cross-team dependencies, mitigating risks, and ensuring alignment between strategic priorities and delivery outcomes. The role also plays a key part in driving Lean-Agile transformation, coaching leaders and teams, and continuously improving delivery practices across the organization.
This position benefits from expertise in biopharma R&D domains and enterprise informatics solution delivery. Success in this role requires extensive collaboration with global teams, strong experience across the end-to-end software development lifecycle, and the ability to influence without authority within a highly matrixed organization.
Roles & Responsibilities
Lead and facilitate Agile Release Train (ART) execution using SAFe principles and Lean-Agile practices.
Drive successful planning and execution of Program Increment (PI) Planning, Scrum of Scrums, Inspect & Adapt workshops, Solution Demos, and other ART ceremonies.
Partner with Product Management, Product Owners, Engineering, Architecture, and business stakeholders to ensure alignment between strategic priorities and execution.
Enable predictable, high-quality delivery by improving flow, removing impediments, managing risks, and resolving cross-team dependencies.
Coach Scrum Masters, Agile teams, Product Managers, and leaders to continuously improve Agile maturity and delivery effectiveness.
Foster a culture of continuous improvement through retrospectives, data-driven decision making, innovation, and Lean thinking.
Monitor ART health using delivery metrics and Agile performance indicators, providing transparent reporting and actionable insights to leadership.
Drive execution of strategic portfolio initiatives across multiple cross-functional teams while balancing business priorities and organizational objectives.
Facilitate collaboration across globally distributed teams to ensure seamless delivery and operational excellence.
Manage and optimize the flow of value through the Agile Release Train using tools such as Program Kanban, Jira, Jira Align, Confluence, and other Agile information radiators.
Coordinate with support, operations, and service teams to ensure successful product releases and issue resolution.
Lead organizational readiness activities for PI Planning, including stakeholder alignment, dependency management, communication, and planning logistics.
Champion Lean-Agile transformation by coaching leaders and influencing organizational change that improves execution and business outcomes.
Support continuous evolution of Agile delivery practices, governance models, and operational excellence across the organization.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients.
Basic Qualifications
Bachelor's degree in Computer Science, Engineering, Biotechnology, Information Technology, or a related discipline.
12–17 years of experience in software delivery, Agile program management, product delivery, or related technology leadership roles.
Must-Have Skills
Strong expertise in Agile methodologies, particularly the Scaled Agile Framework (SAFe) .
Experience serving as a Release Train Engineer, Agile Program Manager, Scrum Master, or similar enterprise Agile leadership role.
Proven experience facilitating PI Planning and other SAFe events across multiple Agile teams.
Strong understanding of Agile software delivery and the end-to-end Software Development Lifecycle (SDLC).
Hands-on experience with Jira, Jira Align, Confluence, and Agile planning/reporting tools.
Experience identifying, managing, and resolving cross-team dependencies, risks, and impediments.
Strong stakeholder management skills with the ability to influence leaders and teams across a global matrix organization.
Excellent analytical, problem-solving, facilitation, and communication skills.
Demonstrated ability to coach teams and leaders while driving continuous improvement and organizational agility.
Demonstrated experience managing data-focused projects, including initiatives involving data platforms, data integration, analytics, or data transformation.
Provide people leadership by coaching, mentoring, and developing team members, fostering a high-performing, collaborative, and accountable culture while supporting individual growth and organizational objectives.
Good-to-Have Skills
Experience within biotechnology, pharmaceutical, healthcare, or other regulated industries.
Understanding of DevOps practices, CI/CD, and Test Automation.
Experience supporting enterprise portfolio planning and Lean Portfolio Management.
Workshop facilitation, organizational change management, and Agile transformation experience.
Professional Certifications
Preferred certifications include:
Certified SAFe Release Train Engineer (RTE)
SAFe Program Consultant (SPC)
PMI Project Management Professional (PMP)
Certified Scrum Professional (CSP) or equivalent Agile certification
Soft Skills
Strong servant leadership and coaching mindset.
Excellent communication, facilitation, and interpersonal skills.
Ability to influence without authority across multiple stakeholder groups.
Strong collaboration and relationship-building capabilities.
Ability to manage multiple priorities in a fast-paced environment.
Strategic thinking with a strong focus on execution and business outcomes.
Commitment to continuous learning and continuous improvement.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans aligned with local market practices.
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Job details
How this role compares
Computed from every other active Information Technology role in our database, not just this employer's listings.
We currently track 225 comparable Manager Information Technology roles across 30 biopharma companies.
Salary context
42 of 225 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 225 comparable roles
+ 11 more countries
Seniority mix
225 of 225 peers have a known seniority level
Therapeutic area mix
0 of 225 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
No peers with a known therapeutic area yet.
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.