Amgen Inc. Posted August 11, 2026

Scientist, Integrated Computational and Experimental Inflammation Discovery

South San Francisco, United States Full time
Drug Discovery & Preclinical Research

Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Scientific

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist, Integrated Computational and Experimental Inflammation Discovery

What you will do

Let’s do this. Let’s change the world. In this vital role you will contribute to Inflammation discovery programs by planning and coordinating project tasks, generating and interpreting high-quality experimental data, and applying computational and AI-enabled approaches to deepen our understanding of disease biology, refine therapeutic hypotheses and support target discovery.

Working with minimal supervision, you will manage defined program components, develop an area of scientific expertise, and communicate data-driven insights that help advance project decisions.

Key Responsibilities:

Plan and coordinate defined project tasks and activities that support target identification, validation, and progression of Inflammation discovery programs.

Design, execute, analyze, and interpret bench/wet lab studies to investigate disease mechanisms and test therapeutic hypotheses with scientific rigor and appropriate urgency.

Apply computational, AI-enabled, and data-analytic approaches to generate mechanistic insights, refine experimental design, and integrate findings across data sources.

Integrate experimental results with published literature, human genetics, clinical observations, and internal or external datasets to inform ongoing project design.

Develop and optimize solutions to technical problems of advanced scope and complexity within an emerging area of expertise.

Collaborate across functions and departments, contributing at the project-team level and building constructive relationships with wet-lab, computational, translational, and drug-discovery partners.

Organize, interpret, document, and present project data and scientific recommendations within work groups, project teams, and internal scientific forums.

Coach or guide others within the work group or project team where appropriate, and contribute to a collaborative culture of scientific curiosity, knowledge sharing, and operational excellence.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The researcher we seek is a Scientist with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 2 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering

OR

Bachelor’s degree and 4 years of experience in Immunology, Cell Biology, Molecular Biology, Pharmacology, Biomedical Sciences, Computational Biology, Bioengineering

Preferred Qualifications:

Advanced and proficient understanding of technical principles, theories, and concepts relevant to inflammation and immunology research.

Experience designing, executing, analyzing, and interpreting experimental studies that support target discovery, validation, or mechanistic biology.

Familiarity with AI-enabled scientific tools, computational biology approaches, advanced data analytics, or multimodal data integration.

Basic knowledge of related or adjacent disciplinary areas, such as translational science, human genetics, clinical biology, drug discovery, or data science.

Demonstrated ability to work under minimal supervision, make independent decisions within a work group, and manage defined project components.

Strong communication skills and the ability to organize, interpret, document, and present scientific or technical information to work groups and project teams.

Experience collaborating across functions or departments and contributing constructively to project-team goals.

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range

123,052.80USD -166,483.20 USD

Job details

Seniority
Not listed
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
South San Francisco, United States
Employment type
Full time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 383 comparable Drug Discovery & Preclinical Research roles across 47 biopharma companies.

383Comparable roles tracked
345Currently active
47Companies hiring similar roles
16Countries represented

Salary context

137 of 383 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Scientist 1, Oncology | Drug Discovery · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Head, Oncology Drug Discovery – San Diego · Novartis $248,500/yr – $461,500/yr
Peer group range $0 – $355,000 (median $165,300)

Where these roles are based

Top locations among the 383 comparable roles

United States303
India17
Germany13
United Kingdom9
Canada9
Switzerland6

+ 10 more countries

Seniority mix

297 of 383 peers have a known seniority level

Senior111
Principal57
Intern/Fellow/Postdoc34
Director26
Associate23
Associate Director21
Senior Director12
Executive/VP8
Manager5

Therapeutic area mix

54 of 383 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology31
Cardiovascular / CVRM10
Immunology6
Neuroscience4
Vaccines & Infectious Disease2
Respiratory1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
AstraZeneca Gaithersburg, Maryland, United States of America Principal
Same function Same country
40%similar
Lilly San Francisco, California, United States of America Executive/VP
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Executive/VP
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Intern/Fellow/Postdoc
Same function Same country
40%similar
Lilly San Diego, California, United States of America Intern/Fellow/Postdoc
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Intern/Fellow/Postdoc
Same function Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Principal Scientist Drug Product Development
AstraZeneca · Gaithersburg, Maryland, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Postdoctoral Researcher in Translational Oncology
Lilly · Indianapolis, Indiana, United States of America · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
40%
Advisor / Senior Advisor, CNS/PNS NAMs – Investigative Toxicology
Lilly · Indianapolis, Indiana, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Director / Sr / Exec Dir - Applied Intelligence for Discovery (AI4D)
Lilly · San Francisco, California, United States of America · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.