Scientist II, Analytical Development

About This Role:

At Biogen, we are advancing science to deliver innovative therapies that transform patients’ lives. We are seeking a Scientist II to join our Analytical Development team as a Liquid Chromatography (LC) Subject Matter Expert (SME) and Analytical Project Lead. This role is pivotal,   leveraging   deep technical   expertise   in LC method development alongside leadership in analytical strategy across synthetics programs. Situated in Cambridge, MA, this lab-based position plays a crucial part in driving forward the development of synthetic drug substances and products, ensuring robust, stability-indicating methods. Your contributions will be vital to our mission, interfacing with various   teams   and shaping the analytical landscape of our drug development efforts.

What   You’ll   Do:

Serve as the LC subject matter expert, leading method development, optimization, qualification, and troubleshooting (HPLC, UHPLC, LC-MS).

Develop robust, stability-indicating methods for synthetic drug substances and products.

Provide technical support to inform analytical   strategy   for development programs from early to late stage.

Collaborate cross- functionally   with CMC, formulation, process development, and quality teams.

Provide oversight of analytical activities at CDMOs, including method validation, transfer, and lifecycle management aligned with regulatory expectations.

Participate in mentoring and knowledge-sharing activities to support analytical capability building within the organization.

Contribute to programs involving emerging modalities (e.g., oligonucleotides and peptides).

Who You Are:

You are enthusiastic about tackling complex analytical challenges to advance the development of small molecule therapeutics and oligonucleotides. You are motivated to learn new techniques and become a subject matter expert. You thrive both independently and collaboratively within a team setting, bringing a passion for scientific innovation and a commitment to excellence.

Required Skills:

Ph.D. with 0-3 years of relevant   experience   in pha r maceu tical   or bio tech se ttings

M.S. with 4+ years of relevant experience in pharmaceutical or biotech settings.

BS with 6+ years of relevant experience in pharmaceutical or biotech   settings

Deep   expertise   in small molecule LC method development, with strong experience in HPLC/UHPLC and familiarity with LC-MS.

Proven ability to lead analytical activities for drug development programs.

Strong knowledge of ICH guidelines and experience working within regulated (GMP/GLP) environments.

Excellent problem-solving, communication, and cross-functional collaboration skills.

Preferred Skills:

Experience with oligonucleotides and/or peptides.

Advanced MS techniques (e.g., LC-MS/MS, HRMS).

Job Level: Management

Additional Information

The base compensation range for this role is: $117,000.00-$157,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:

Medical, Dental, Vision, & Life insurances

Fitness & Wellness programs including a fitness reimbursement

Short- and Long-Term Disability insurance

A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)

Up to 12 company paid holidays + 3 paid days off for Personal Significance

80 hours of sick time per calendar year

Paid Maternity and Parental Leave benefit

401(k) program participation with company matched contributions

Employee stock purchase plan

Tuition reimbursement of up to $10,000 per calendar year

Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.  Read on  to learn more about Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.