Biogen Posted August 11, 2026

Principal Analyst, Operations and Health Systems Research

Cambridge, United States Full time
Principal

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About this opportunity

About This Role

Biogen studies highly complex, devastating, and burdensome diseases and there are still significant challenges in how we understand and treat them.

In the Quantitative Sciences Development Organization we aspire to transform patients’ lives by accelerating disease research using best in breed and emerging techniques. Leveraging applied machine learning and emerging technologies, we drive solutions to advance research, clinical care, and patient empowerment.

We stand with our colleagues across Biogen developing pioneering treatments. We believe that now, more than ever, biology and technology should go hand-in-hand to better meet patient needs, while enabling a shift towards more prevention-focused, affordable, and equitable care.

What You’ll Do

As a Principal Analyst, Operations and Health Systems Research, you will:

Design, develop, and implement complex end-to-end data pipelines, engineer features and forecasting models to understand the intersection of health systems utilization and clinical research

Integrate real world data sources in order to build epidemiological and disease forecasting models used to support decision-making for clinical trial operations

Leverage methods from operations research such as constraints-based optimization, linear and non-linear programing, simulation and network modeling to understand participant, investigator, and sponsor behaviors that drive risk, benefit, and uncertainty in clinical trial outcomes.

Generate evidence and communicate results, including at conferences and in peer-reviewed publications for audiences in the therapeutic area of interest, sensor science, machine learning and operations research.

Support integration, design and development of novel measures, models, and metrics to assess model validity and performance across the model lifecycle.

Who You Are

You are passionate about exploring and establishing new methods for looking at data across devices, applications, data streams, and diseases. You love figuring out how to create mathematical and statistical models that relate human biology, clinical development, and sensor technology to business outcomes and patient needs.

Required Skills

>= 5 years Pharma/Biotech/Tech/Healthcare industry experience, alternatively extensive experience in academic/clinical centers of excellence

Expertise in leveraging electronic health records and other data sources derived from clinical care via state-of-the-art methodologies, programming languages, and tools

Experience working on machine learning operations research, and data science problems using formal software development lifecycle approaches and best practices as part of a software delivery organization

Profound experience in data science, machine learning, operations research and data engineering programming using python/R and higher-level libraries such as numpy, pandas, scipy, statsmodels, scikit-learn, Google OR Tools, TensorFlow/PyTorch, pyspark, tidyverse, sparklyr, mlr, tidymodels or similar

Strong familiarity with simulation and forecasting models used by business stakeholders and experience in communicating results and improving models given feedback from end-users

Preferred Skills

Experienced in communicating and building consensus on highly technical or sensitive information with technology and business teams

Experience iterating through UI/UX patterns, data visualization, and front-end interactions and balancing across conflicting stakeholder preferences

Formal application of principles of empirical science including statistical modeling, design of experiments, and hypothesis formulation and testing

Advanced degree in public health, epidemiology, public health economics, operations research or a similar discipline

Job Level: Management

Additional Information

The base compensation range for this role is: $141,000.00-$188,000.00

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:

Medical, Dental, Vision, & Life insurances

Fitness & Wellness programs including a fitness reimbursement

Short- and Long-Term Disability insurance

A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)

Up to 12 company paid holidays + 3 paid days off for Personal Significance

80 hours of sick time per calendar year

Paid Maternity and Parental Leave benefit

401(k) program participation with company matched contributions

Employee stock purchase plan

Tuition reimbursement of up to $10,000 per calendar year

Employee Resource Groups participation

Why Biogen?

We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired.  Read on  to learn more about Biogen.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Job details

Seniority
Principal
Function
Not listed
Therapeutic area
Not listed
Location
Cambridge, United States
Employment type
Full time

How this role compares

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