GlaxoSmithKline LLC Posted July 23, 2026

OT Systems Engineer

King of Prussia, United States Full time
Manufacturing & CMC

GlaxoSmithKline LLC is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Provide direct engineering and technical support of site operating technology (OT) networks and systems.  Evaluate and develop technology, plan and implement modifications, maximize network/system security and performance, and ensure operability of various controls, digital, and execution systems, and their integrations.

This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following:

Provide maintenance and lifecycle support for site automation/digital applications; with a focus on  systems administration, virtualization, cross-platform integrations, and digital compliance.

Support and optimize the application of cybersecurity controls within the OT environment, to include (but are not limited to) user access management, system hardening/patching, anti-virus scanning and system configuration management.

Troubleshoot and diagnose problems within the OT network infrastructure, including virtualization hosts, server/system hardware, network switches, PLC/DCS controllers, and network devices.

Provide technical support related to interfacing of devices using serial, bus interfaces, and other integration communication protocols (e.g. Profibus, Ethernet I/P, OPC, ODBC)

Partner within the site digital/automation teams in all facets – development, planning, execution, and support.  Provide within these teams elevated level of support in your areas of technical responsibility and offer additional capacity as needed.

Become capable with site automation and digital systems such as Emerson DeltaV, Emerson Syncade, Rockwell PLCs, and Siemens Desigo.

Drive continuous improvement and problem solving across disciplines and functions within the site.  This should manifest in improved ways of working, procedures and documentation, technical design, cybersecurity, performance, capability, and operating model.

Work in a way that models respect for employee safety, EHS, quality, compliance, data integrity, and GSK standards.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

BS/BA in engineering, life sciences or software.

1 year of experience programming and troubleshooting with any of the following: Emerson DeltaV, Rockwell PLCs, Siemens Desigo. Experience with the administration, maintenance and upkeep of process control systems.

OR in lieu of education 3+ years of experience programming and troubleshooting with any of the following: Emerson DeltaV, Rockwell PLCs, Siemens Desigo.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

Additional experience in design, programming, start-up, and troubleshooting of process control systems, building automation systems, PLCs, and/or instrumentation.

Experience in systems/account administration, network design, and server troubleshooting.

Experience in the design, configuration, and testing of cross-platform system integrations using communication protocols (e.g. OPC, ODBC, Ethernet-IP).

Experience working within a virtualized environment (Microsoft Hyper-V) is preferred.

Knowledge in firewall management, OT/IT integration and cyber security standards is preferred.

Experience working across the ISA95 levels (e.g. Control, MES, Enterprise) to apply/enforce proper network design and segmentation.

Experience working in a GMP environment, especially computer system validation and data integrity.

Ability to diagnose problems, generate options, prioritize issues, select optimal solutions, and implement decisions/resolve problems is required.

A demonstrated ability to interact well with peers and senior personnel in multidisciplinary teams involving scientific, engineering, and operational disciplines.

#LI-GSK

Skills

Asset Life Cycle Management, Data Integrity, Digital Fluency, GxP Regulations, Lean Management, Manufacturing Technologies, Pharmaceutical Manufacturing, Problem Solving, Risk Awareness, Standards Compliance

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at -  [email protected]

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job details

Seniority
Not listed
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
King of Prussia, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 1527 comparable Manufacturing & CMC roles across 125 biopharma companies.

1527Comparable roles tracked
1434Currently active
125Companies hiring similar roles
44Countries represented

Salary context

456 of 1527 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Scientist II – CMC Developmental Sciences · AbbVie $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $540,400 (median $140,000)

Where these roles are based

Top locations among the 1527 comparable roles

United States781
India104
Germany74
Singapore67
France64
Ireland54

+ 38 more countries

Seniority mix

705 of 1527 peers have a known seniority level

Senior251
Manager165
Principal79
Associate68
Director64
Associate Director44
Senior Director21
Intern/Fellow/Postdoc8
Executive/VP5

Therapeutic area mix

7 of 1527 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease6
Oncology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
Alexion New Haven, Connecticut, United States of America
Same function Same country
40%similar
AstraZeneca Cambridge, Massachusetts, United States of America Director
Same function Same country
40%similar
Alexion New Haven, Connecticut, United States of America
Same function Same country
40%similar
40%similar
Lilly Boston, Massachusetts, United States of America Associate
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Senior Director
Same function Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Scientist II, LC Development, Biologics Analytical Development
Alexion · New Haven, Connecticut, United States of America · Seniority not listed
Function Therapeutic area Seniority Country
40%
Director, Global Regulatory Affairs – Chemistry, Manufacturing and Controls (CMC), Platform Innovation – Synthetic Peptides and Oligonucleotides
Lilly · Indianapolis, Indiana, United States of America · Director
Function Therapeutic area Seniority Country
40%
Senior/Principal Scientist, Bioprocess Purification Development
Lilly · Indianapolis, Indiana, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Senior Principal Scientist - Bioanalytical Research
Lilly · Louisville, Colorado, United States of America · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.