Amgen Inc. Posted August 4, 2026

Observational Research Senior Manager- Inflammation

Remote, United States Full time
Clinical Development Manager

Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Research

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Observational Research Senior Manager

What you will do

Let’s do this. Let’s change the world. The Observational Research Senior Manager will be a member of the Inflammation / Rare Disease team within CfOR and will be responsible for generating insights and building collaborations and capabilities to advance the use of real-world evidence related to disease state epidemiology (e.g., global burden, natural history), treatment patterns, and medication safety.

Responsibilities:

Leading the design, execution and delivery of RWE studies and analyses to support evidence generation to support Amgen’s pipeline and in-line medicines

Contributing to the development and implementation of innovative analytic methods, capabilities and tools to enable rapid, scalable and reproducible RWE

Leveraging real-world data and CfOR analytic approaches to advise high-value business decisions for multiple collaborators.

Communicating significant scientific information to a variety of audiences

Building collaborations, promoting awareness, understanding and use of observational research methods with key partners.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Observational Research professional we seek has these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of related epidemiology and research experience OR

Master's degree and 6 years of related research and scientific experience OR

Bachelor's degree and 8 years of related research and scientific experience OR

Bachelor's degree and 10 years of related research and scientific experience OR

High School diploma / GED and 12 years of related research and scientific experience

Preferred Qualifications:

Doctorate in Epidemiology or other subject with high observational research content.

Experience in the design, execution and analysis of observation research studies within Pharmaceutical and/or Public Health settings.

Experience in research to support drug development.

Experience working with secondary data systems including administrative claims, EMR and registries.

Experience in observational research project planning and management.

Excellent communication, presentation and interpersonal skills.

Experience working with and leading multi-disciplinary teams.

Experience in Dermatology research and/or other inflammation therapeutic areas.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

. Salary Range

148,265.50USD -200,594.50 USD

Job details

Seniority
Manager
Function
Clinical Development
Therapeutic area
Not listed
Location
Remote, United States
Employment type
Full time

How this role compares

Computed from every other active Clinical Development role in our database, not just this employer's listings.

We currently track 266 comparable Manager Clinical Development roles across 45 biopharma companies.

266Comparable roles tracked
230Currently active
45Companies hiring similar roles
29Countries represented

Salary context

64 of 266 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Clinical Trials Data Associate (P1) · Lilly $79,206/yr – $91,087/yr
Highest disclosed · Statistical Advisor · Gilead Sciences, Inc. $226,185/yr – $292,710/yr
Peer group range $85,146 – $259,448 (median $178,650)

Where these roles are based

Top locations among the 266 comparable roles

United States101
India50
China14
United Kingdom13
Poland13
Germany10

+ 23 more countries

Seniority mix

266 of 266 peers have a known seniority level

Manager145
Associate Director73
Associate48

Therapeutic area mix

26 of 266 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology9
Immunology6
Cardiovascular / CVRM6
Neuroscience3
Dermatology & Aesthetics1
Ophthalmology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Lilly Stamford, Connecticut, United States of America Manager
Same function Same seniority Same country
60%similar
Lilly Indianapolis, Indiana, United States of America Manager
Same function Same seniority Same country
60%similar
AbbVie Manager
Same function Same seniority Same country

Open in 3 locations

Irvine, United StatesNorth Chicago, United StatesFlorham Park, United States
60%similar
AbbVie Manager
Same function Same seniority Same country

Open in 4 locations

North Chicago, United StatesFlorham Park, United StatesIrvine, United StatesSouth San Francisco, United States
60%similar
Amgen Inc. Remote, United States Manager
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Manager, Clinical Development Trial Lead (CDTL)
Lilly · Stamford, Connecticut, United States of America · Manager
Function Therapeutic area Seniority Country
60%
Senior Manager, Clinical Data Systems
AbbVie · North Chicago, IL · Manager
Function Therapeutic area Seniority Country
60%
Manager, Clinical Data and Reporting Standards - SDTM Programming (Hybrid)
AbbVie · Florham Park, NJ · Manager
Function Therapeutic area Seniority Country
60%
Observational Research Senior Manager (Bone)
Amgen Inc. · Remote, United States · Manager
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.