AstraZeneca Posted August 3, 2026

Manager Site Operations, Facilities Maintenance, Second shift

Gaithersburg, Maryland, United States of America Full time
Manufacturing & CMC Manager

AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Join a collaborative, tech-enabled team using data, analytics, and current engineering to boost asset performance and sustainability. You’ll turn metrics into action, lead a high-performing team, and deliver projects that strengthen infrastructure and reduce environmental impact, shift after shift.

What you’ll do:

Facilities and utilities: Keep campus-critical systems running through preventive, predictive, and corrective maintenance; ensure uninterrupted utilities for cGMP operations and respond to BMS alarms 24/7.

Maintenance excellence: Build and optimize PM programs, follow KPIs, and lift uptime and asset health.

Work management: Partner with Planning and Scheduling; drive accurate CMMS (SAP) data and effective work execution.

Materials and spares: Set stocking and reordering strategies to protect reliability.

Projects: Lead facilities capital projects from plan to handover, on scope, budget, schedule, and sustainability targets.

Construction and commissioning: Oversee reviews, permitting, commissioning, and collaborator communications for safe, smooth delivery.

Vendors and contracts: Source, debate, and lead to quality and value.

Compliance and quality: Ensure cGxP/FDA/SOP adherence; handle changes, deviations, and training/qualification.

Investigations and safety: Lead root cause analyses; champion SHE, hazard assessments, training, and PPE.

Sustainability and CI: Cut carbon, waste, and cost; optimize energy and resources with partner teams.

People leadership: Coach technicians, engineers, and contractors; build capability and strong cross-functional ties.

Site stewardship: Contribute to site planning, procedures, budgets, schedules, and performance metrics; brief senior stakeholders.

Minimum requirements:

Bachelor's  in Engineering, Facilities Management, or a related technical discipline. Equivalent work experience (5 years) may be considered.

5+ years of experience in Maintenance, Engineering, or Facilities Management.

Experience with maintenance software, AutoCAD, and other specialized programs used in operations.\

Maintenance leadership on sophisticated, cGMP-related infrastructure with 24/7 reliability expectations.

Strength in utilities, BMS monitoring, CMMS (SAP), planning/scheduling, and KPI-driven improvement.

Experience delivering facilities capital projects and managing vendors/contracts.

Proven safety, cGxP/FDA compliance, and quality systems ownership.

Track record in investigations (RCA/CAPA) and team development.

Strategic influence across departments with budget, schedule, and policy accountability.

Desirable skills:

cGMP lab/pilot plant/manufacturing experience; second-shift or 24/7 leadership.

Certifications (PMP, CMRP), Lean/Six Sigma, and energy/sustainability (LEED, ISO 14001).

Analytics for BMS/CMMS to enable predictive maintenance and asset health.

Managing multi-contractor environments and long-term service agreements.

Why AstraZeneca Power the infrastructure that enables breakthrough science. Work in a diverse, inclusive culture that blends cutting-edge tech with real-world impact. Tap a global network, share ideas, and turn data into better reliability, sustainability, and, ultimately, patient outcomes. We value kindness and ambition, and we’ll trust you to shape how a complex site runs.

The annual base pay (or hourly rate of compensation) for this position ranges from $ 89,874.40 - $134,811.60.  Our positions offer eligibility for various incentives, an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Ready to lead? If you’re excited to run second-shift operations that keep mission-critical facilities safe, compliant, and always on, and to turn metrics into meaningful progress, apply now.

Date Posted

03-Aug-2026

Closing Date

16-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Job details

Seniority
Manager
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Gaithersburg, Maryland, United States of America
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 276 comparable Manager Manufacturing & CMC roles across 50 biopharma companies.

276Comparable roles tracked
257Currently active
50Companies hiring similar roles
23Countries represented

Salary context

95 of 276 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Associate Operator - 2nd Shift · Mylan Technologies, Inc. $30,000/yr – $49,000/yr
Highest disclosed · Associate Director Packaging Development · Gilead Sciences, Inc. $182,070/yr – $235,620/yr
Peer group range $39,500 – $208,845 (median $169,000)

Where these roles are based

Top locations among the 276 comparable roles

United States171
India39
Ireland14
Singapore7
China's Mainland6
Netherlands5

+ 17 more countries

Seniority mix

276 of 276 peers have a known seniority level

Manager164
Associate68
Associate Director44

Therapeutic area mix

0 of 276 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

No peers with a known therapeutic area yet.

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
AbbVie Manager
Same function Same seniority Same country

Open in 4 locations

North Chicago, United StatesIrvine, United StatesSouth San Francisco, United StatesWorcester, United States
60%similar
AbbVie North Chicago, IL Manager
Same function Same seniority Same country
60%similar
AbbVie Manager
Same function Same seniority Same country

Open in 2 locations

Waltham, United StatesNorth Chicago, United States
60%similar
AbbVie North Chicago, IL Manager
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Manager
Same function Same seniority Same country
60%similar
Sanofi Vaccines US Inc. Swiftwater, United States Manager
Same function Same seniority Same country

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Manager, Product Development Quality Assurance (CMC Product Lead)
AbbVie · North Chicago, IL · Manager
Function Therapeutic area Seniority Country
60%
Senior Manager, Product Development Quality Assurance (CMC Product Lead)
AbbVie · Worcester, MA · Manager
Function Therapeutic area Seniority Country
60%
Senior Manager Regulatory Affairs, Chemistry, Manufacturing and Controls (CMC)
AbbVie · North Chicago, IL · Manager
Function Therapeutic area Seniority Country
60%
Manager of Automation
Sanofi Vaccines US Inc. · Swiftwater, United States · Manager
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.