Exec Director, Viral Vector Process Development

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.

Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description

This role is accountable for end-to-end viral vector development, from construct design through clinical and commercial manufacturing support, and serves as a key partner across Research, Product Teams, Technical Operations, and Analytical functions.

The leader will balance deep technical expertise with executive-level influence, ensuring robust, scalable vector platforms while building a high-performing organization capable of supporting both ex vivo and emerging in vivo applications.

Reporting & Location

Reports to: SVP, Global Head of Process Development

Location: Santa Monica, CA Or Oceanside, CA

On-site presence required

Key Responsibilities

Technical & Scientific Leadership

Accountable for technical strategy for viral vector platforms across clinical and commercial scale, including complex tech transfers, external manufacturing partnerships, and late‑stage manufacturing readiness.

Provide deep expertise in lentiviral vector (LVV) design, including construct architecture, promoter selection, and transgene optimization

Lead viral vector process development, including: Upstream production systems (transient and stable)

Downstream purification and recovery operations

Drive process scale-up and technology transfer to clinical and commercial manufacturing sites (internal and external)

Oversee LVV life cycle management and  manufacturing support capabilities

Lead initiatives to improve viral vector productivity, robustness, and cost of goods

Advance next-generation capabilities, including: In vivo viral vector development

Platform innovations and emerging delivery technologies

Cross-Functional & Product Development Leadership

Ensure viral vector development decisions are optimized across the full cell therapy value chain, from transduction efficiency and cell performance to manufacturing robustness and CMC sustainability.

Provide strategic leadership for viral vector on cross-functional Product Teams

Partner closely with: Research to translate early concepts into developable and scalable vector designs

T cell process development to align vector performance with cellular outcomes

Analytical development to ensure appropriate characterization and control strategies

Contribute to integrated product development, ensuring vector design and process decisions align with clinical and commercial objectives

Drive alignment across functions in a matrixed environment, balancing competing priorities while maintaining product focus

CMC & Regulatory Engagement

Strong working knowledge of cGMP regulations and compliance systems related to viral vector development, including inspection readiness, audit support, and direct engagement with regulatory agencies.

Contribute to LVV CMC strategies, including phase-appropriate viral vector development and scale-up approaches

Support regulatory filings and health authority interactions as a technical expert

Provide input into comparability strategies for process changes, site transfers, and lifecycle evolution of LVV

Organizational Leadership & Talent Development

Provide leadership oversight for viral vector development laboratories and GMP‑adjacent environments, ensuring facility readiness, compliance, and operational excellence in support of clinical and commercial programs.

Demonstrated experience leading large organizations within a highly matrixed cell and gene therapy environment.

Build, lead, and scale a high-performing viral vector development organization

Recruit, develop, and retain top scientific and leadership talent

Coach and develop future leaders, ensuring depth and succession within the organization

Foster a culture of: Scientific rigor and accountability

Ownership and execution

Collaboration and transparency

Leadership, Communication & Executive Influence

Demonstrate strong executive presence, with the ability to clearly communicate complex technical concepts to diverse audiences

Influence decision-making at senior leadership and governance levels, providing clear, balanced perspectives on risks, trade-offs, and options

Drive clarity in ambiguity, enabling teams to make timely and well-informed decisions

Communicate effectively across: Technical teams

Cross-functional stakeholders

Executive leadership

Build credibility as a trusted partner and advisor, both internally and externally

Represent the organization in external collaborations, partnerships, and industry forums

Basic Qualifications

PhD in Biochemical Engineering, Molecular Biology, Virology, or related field with 15+ years of experience (or MS with 18+ years)

Extensive experience in viral vector development and manufacturing support for cell and/or gene therapy

Demonstrated expertise in LVV and/or RVV systems

End-to-end experience from early development through commercialization

Strong understanding of: Viral vector development across phases

Analytical characterization strategies

Manufacturing and tech transfer considerations for viral vector

Experience leading cell therapy programs (e.g., CAR-T)

Proven ability to lead in a highly matrixed, cross-functional environment

Track record of influencing portfolio and strategic decisions for successful drug development

Preferred Qualifications

Exposure to in vivo gene delivery platforms

Sound knowledge in RVV development and CMC aspects

Leadership Attributes

Enterprise mindset, prioritizes product and patient impact over functional optimization

Technical depth with judgment, knows when to go deep and when to elevate

Clarity and decisiveness, simplifies complexity into actionable direction

Talent builder, develops leaders, not just teams

Strong influencing skills across matrixed environments

Ability to integrate strategy with execution

The salary range for this position is: $255,425.00 - $330,550.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .

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Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex , age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact  [email protected] for assistance.

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Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the  legal duty to furnish information; or (d) otherwise protected by law.

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