ERP/SAP Change Owner

Career Category

Project Management

Job Description

Join Amgen’s Mission of Serving Patients

Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier,   fuller   and longer. We discover, develop,   manufacture   and deliver innovative medicines to help millions of patients. Amgen helped   establish   the biotechnology industry more than 40 years ago and   remains   on the   cutting-edge   of innovation, using technology and human genetic data to push beyond   what’s   known today.

At Amgen, if you feel like   you’re   part of something bigger,   it’s   because you are. Our shared mission   to serve patients living with serious illnesses   drives all that we do.

Since 1980,   we’ve   helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team,   you’ll   help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that   lay   within them,   you’ll   thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you   will do

Let’s   do this.   Let’s   change the world.

In this critical role, you will serve as the end-to-end Change Owner for SAP / ERP   portfolio , ensuring that all system changes are planned, assessed, implemented,   validated , and released in compliance with   GxP   regulations, Amgen IT-QMS   and change management process   aligned to   global   best practices .

You will partner closely with Business, ERP   product   delivery teams, Validation, and Quality to enable risk-based, audit-ready, and efficient change execution across Amgen’s SAP landscape.

Roles & Responsibilities:

Act as the single point of accountability for SAP ERP changes across projects, enhancements, fixes, and operational maintenance.

Own and execute the change lifecycle including:

Change initiation and classification

Impact and risk assessment

Approval coordination ( Change managers,   Business,   SMEs,   Quality, CAB)

Implementation oversight

Post-implementation verification and closure

Ensure all SAP changes   comply with :

21 CFR Part 11 /   EU Annex 11 regulations

ALCOA+ data integrity principles

GAMP 5 and CSA (Computer Software Assurance)

Partner with   Quality and Compliance   to:

Assess validation impact of changes

Assess   required validation deliverables

Ensure traceability between requirements, risks, testing, and release

Support SAP platforms including ECC, S/4HANA, BTP, GRC, Solution   Manager ( Solman) , integrations, and boundary systems.

Ensure changes   maintain   effective controls for:

User access and segregation of duties

Audit trails and logging

Configuration vs. customization decisions

Coordinate with SAP   development,   functional , testers and   SME’s   to ensure   timely   and compliant   deployment   of changes.

Support release planning, cutover activities, and   hypercare   as   required .

Maintain audit-ready documentation and evidence for change, validation, incident, and deviation activities.

Proactively   identify   opportunities to simplify   and   optimize   change processes, reduce rework, and improve cycle time while   maintaining   quality and   compliance.

Contribute to continuous improvement initiatives   across the Change management , including adoption of digital validation, automation, and standardized templates.

Support internal and external audits by providing change-related evidence and responding to audit inquiries

What we expect   of   you

We are all different, yet we all use our unique contributions to serve patients.

Basic Qualifications and Experience:

Master’s degree and   3 +   years of Computer Science, IT /Lifesciences Change Management with   Computerized systems Validation/   Assurance ( CSV/CSA)   understanding   in a   G x P   regulated environment   OR

Bachelor’s degree and   5 +   years of Computer Science,   T /Lifesciences Change Management with   Computerized systems Validation/Assurance   understanding   in a   G x P   regulated environment   OR

Diploma and   8 +   years of Computer Science,   I T /Lifesciences Change Management with   Computerized   systems   Validation/Assurance   understanding   in a   G x P   regulated environment .

Hands-on experience supporting SAP ERP systems in a   GxP -regulated environment

Strong working knowledge of:

IT Change Management

Strong understanding of SAP ERP landscapes

Validation and compliance processes

Regulatory requirements (21 CFR Part 11, Annex 11, ALCOA+, GAMP 5)

Experience working within structured SDLC , Agile , Transport Management   and IT-QMS frameworks.

Preferred Qualifications:

Experience supporting SAP transformation initiatives ( Ex:   R/3 to ECC and/or   ECC   to   S/4HANA upgrades ).

Familiarity with   CSA-aligned, risk-based validation approaches   and   Hands on experience preparing change and validation documentation .

Experience working with ITSM and change management tools ( Ex ., ServiceNow , Solman ).

Exposure to audits or inspections supporting SAP systems.

Experience working in global, matrixed teams.

Professional Certifications

Scrum Master   or equivalent

ITIL / Change Management certification

Soft Skills:

S trong   sense of ownership and accountability

Excellent communication and stakeholder-management skills

Ability to balance compliance requirements with business agility

Structured, detail-oriented, and risk-aware mindset

Comfortable working across Business, IT, and Quality teams

What you can expect   of   us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture,   we’ll   support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

EQUAL OPPORTUNITY STATEMENT

Amgen is an Equal Opportunity employer and will consider you without regard to your race,   color , religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We   Reasonable accommodation will be provided to individuals with disabilities to   participate   in the job application or interview process and to perform essential job functions.

Apply now

F or a career that defies imagination

Objects in your future are closer than they appear. Join us   at   careers.amgen.com

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