Novartis Posted July 22, 2026

Commercial Portfolio Head

Prague, Czech Republic Regular
Commercial & General Management

Novartis is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

#LI-Hybrid Location: Prague, Czech RepublicThis role is based in Prague, Czech Republic. Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.The Commercial Portfolio Head maximises portfolio value generation and access through innovative go-to-market models, commercial partnerships, and lifecycle management. The role ensures efficient collaboration with above- and in-country stakeholders to execute strategies effectively within resource-constrained environments.

Key responsibilitiesIdentify, evaluate, negotiate, and manage strategic partnerships and alliances to enhance portfolio value and ensure long-term mutual benefit.Lead and scale international collaboration projects, assessing opportunities for expansion at regional and global levels.Drive digital marketing execution including channel optimization, content governance, and leveraging digital assets to support brand performance.Collaborate with TA Heads and cross-functional teams to align digital strategies and maximize synergy across priority brands.Own lifecycle management strategies including LoE planning, brand onboarding, and implementation of late-stage tactics to sustain value.Coordinate cross-functional collaboration (Legal, Finance, Supply Chain, Regulatory) to anticipate and manage post-LoE erosion and operational transitions.Manage portfolio financials including budgeting, forecasting, and performance monitoring aligned with investment guidelines.Monitor brand performance and market trends, enabling data-driven decisions and performance vigilance across the portfolio.Ensure operational excellence by managing ad hoc business requirements, regulatory alignment, and supply continuity to minimize stock-outs and inefficiencies.Lead cross-functional teams to execute priorities while fostering collaboration across complex stakeholder environments.Build and develop high-performing teams, driving talent development, succession planning, and a strong performance culture.Role model Novartis leadership behaviors, driving transformation, accountability, and a growth mindset across the organization.RequirementsUniversity degree in science or business; advanced degree preferred; fluent English required with local language desirable; 10+ years leadership experience in pharma or life sciences.Proven track record of P&L ownership and commercial portfolio management.Extensive experience managing mature brand portfolios including lifecycle management and LoE strategies.Strong expertise in building and managing partnerships (co-promotion, distribution, licensing) with measurable outcomes.Solid understanding of digital marketing in regulated environments, including content governance and performance analytics.Proven ability to lead cross-functional teams and navigate complex stakeholder ecosystems.Strong strategic decision-making capabilities with prioritization frameworks and resource optimization skills.Demonstrated matrix leadership with experience building high-performing teams and driving talent development.Enterprise mindset with focus on long-term portfolio value and sustainability.Strong results orientation with disciplined resource management and ROI focus.Benefits & RewardsAt Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.Expected Annual Base Salary Range for role: 2,094,050.00 to 3,888,950.00 CZK The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.Read our brochure to learn more about our global total rewards offering: https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdfNote: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process.Monthly pension contribution matching your individual contribution up to 3% of your gross monthly base salary; Risk Life Insurance (full cost covered by Novartis); 5-week holiday per year; (1 week above the Labour Law requirement) ; 4 paid sick days within one calendar year in case of absence due to sickness without a medical sickness report; Cafeteria employee benefit program – choice of benefits from Benefit Plus Cafeteria in the amount of 17,500 CZK per year; Meal vouchers in amount of 105 CZK for each working day (full tax covered by company); MultiSport Card; Find out more about Novartis Business Services: https://www.novartis.cz/Commitment to Diversity and Inclusion / EEO paragraphNovartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to [email protected] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Job details

Seniority
Not listed
Function
Commercial & General Management
Therapeutic area
Not listed
Location
Prague, Czech Republic
Employment type
Regular

How this role compares

Computed from every other active Commercial & General Management role in our database, not just this employer's listings.

We currently track 29 comparable Commercial & General Management roles across 6 biopharma companies.

29Comparable roles tracked
12Currently active
6Companies hiring similar roles
8Countries represented

Salary context

4 of 29 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Associate Director, PDM Strategy · Gilead Sciences, Inc. $182,070/yr – $235,620/yr
Peer group range $208,845 – $278,850 (median $262,224)

Where these roles are based

Top locations among the 29 comparable roles

United States18
Japan3
Poland2
Spain2
Romania1
South Korea1

+ 2 more countries

Seniority mix

22 of 29 peers have a known seniority level

Director7
Associate Director7
Senior Director3
Manager3
Executive/VP2

Therapeutic area mix

6 of 29 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology3
Vaccines & Infectious Disease2
Cardiovascular / CVRM1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

25%similar
AstraZeneca Wilmington, Delaware, United States of America Director
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

25%similar
Novartis Bucuresti, Romania
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

25%similar
Gilead Sciences, Inc. Foster City, United States Senior Director
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

25%similar
Gilead Sciences, Inc. Foster City, United States Director
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

25%similar
Gilead Sciences, Inc. Foster City, United States Associate Director
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

25%similar
Gilead Sciences, Inc. Foster City, United States Executive/VP
Same function

Matched on job function only -- seniority, specialty, and location weren't confirmed as aligned.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

25%
Director, US Forecasting & Analytics– Vaccines & Immune Therapies
AstraZeneca · Wilmington, Delaware, United States of America · Director
Function Therapeutic area Seniority Country
25%
Director, PDM Strategy
Gilead Sciences, Inc. · Foster City, United States · Director
Function Therapeutic area Seniority Country
25%
Business Excellence Lead - Huntington's Disease
Novartis · East Hanover, United States · Seniority not listed
Function Therapeutic area Seniority Country
25%
Japan Project Head (Vaccines)
Sanofi KK (Japan) · Tokyo, Japan · Seniority not listed
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.